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SETMAR antibody

SETMAR Reactivity: Human IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7262651
  • Target See all SETMAR Antibodies
    SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
    Reactivity
    • 20
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 17
    • 2
    • 1
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETMAR antibody is un-conjugated
    Application
    • 9
    • 5
    • 4
    • 3
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human SETMAR (NP_006506.3).
    Isotype
    IgG
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  • Application Notes
    IF 1:20-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
    Alternative Name
    SETMAR (SETMAR Products)
    Synonyms
    HsMar1 antibody, METNASE antibody, Mar1 antibody, 5830404F24Rik antibody, Etet2 antibody, SETMAR antibody, zgc:172212 antibody, SET domain and mariner transposase fusion gene antibody, SET domain without mariner transposase fusion antibody, histone-lysine N-methyltransferase SETMAR antibody, SETMAR antibody, Setmar antibody, LOC470738 antibody, setmar antibody, LOC703880 antibody, LOC100447656 antibody, LOC100586616 antibody
    Background
    This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
    Gene ID
    6419
    UniProt
    Q53H47
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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