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MUS81 antibody

MUS81 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7262745
  • Target See all MUS81 Antibodies
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Reactivity
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 10
    • 2
    • 1
    • 1
    This MUS81 antibody is un-conjugated
    Application
    • 8
    • 6
    • 4
    • 3
    Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human MUS81 (NP_079404.3).
    Isotype
    IgG
    Top Product
    Discover our top product MUS81 Primary Antibody
  • Application Notes
    IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MUS81 (MUS81 Endonuclease Homolog (MUS81))
    Alternative Name
    MUS81 (MUS81 Products)
    Synonyms
    CG3026 antibody, Dmel\\CG3026 antibody, EG:BACR7A4.16 antibody, MUS81 antibody, GB15332 antibody, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antibody, ATMUS81 antibody, F6I18.220 antibody, F6I18_220 antibody, MMS AND UV SENSITIVE 81 antibody, SLX3 antibody, slx3 antibody, 1200008A18Rik antibody, AI182501 antibody, AW045863 antibody, wu:fc26g01 antibody, zgc:66489 antibody, zgc:91801 antibody, CG3026 gene product from transcript CG3026-RA antibody, MUS81 structure-specific endonuclease subunit antibody, crossover junction endonuclease MUS81 antibody, Restriction endonuclease, type II-like superfamily protein antibody, Mus81p antibody, Holliday junction resolvase subunit Mus81 antibody, MUS81 protein antibody, hypothetical protein antibody, mus81 antibody, MUS81 antibody, LOC725951 antibody, Mus81 antibody, CAALFM_C600540WA antibody
    Background
    This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
    Gene ID
    80198
    UniProt
    Q96NY9
    Pathways
    DNA Damage Repair
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