EPS15L1 antibody

Catalog No. ABIN7263849

Product Details anti-EPS15L1 Antibody

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS15L1 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human EPS15L1 (NP_001245304.1).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EPS15L1

Target: EPS15L1 (Epidermal Growth Factor Receptor Pathway Substrate 15-Like 1 (EPS15L1))

Alternative Name: EPS15L1 (EPS15L1 Products)

Synonyms: Eps15R antibody, XEps15R antibody, EPS15R antibody, 9830147J04Rik antibody, AI593686 antibody, Eps15-rs antibody, epidermal growth factor receptor pathway substrate 15-like 1 S homeolog antibody, epidermal growth factor receptor pathway substrate 15 like 1 antibody, epidermal growth factor receptor pathway substrate 15-like 1 antibody, eps15l1.S antibody, EPS15L1 antibody, Eps15l1 antibody

Background: Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Molecular Weight:

Observed_MW: 110 kDa

Calculated_MW: 66 kDa/83 kDa/94 kDa/99 kDa

Gene ID: 58513

UniProt: Q9UBC2