PLOD1 antibody

Catalog No. ABIN7263961

Product Details anti-PLOD1 Antibody

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLOD1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human PLOD1 (NP_000293.2).

Isotype: IgG

Application Details

Application Notes: IF 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLOD1

Target: PLOD1 (Procollagen-Lysine,2-Oxoglutarate 5-Dioxygenase 1 (PLOD1))

Alternative Name: PLOD1 (PLOD1 Products)

Synonyms: EDS6 antibody, LH antibody, LH1 antibody, LLH antibody, PLOD antibody, Plod antibody, procollagen-lysine antibody, 2410042F05Rik antibody, AI854890 antibody, AV007929 antibody, Lh1 antibody, plod1 antibody, ik:tdsubs_rzpd609-29b19 antibody, plod antibody, wu:fc29c10 antibody, wu:fc95g08 antibody, wu:fi18a05 antibody, zgc:152876 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 antibody, procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 L homeolog antibody, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a antibody, PLOD1 antibody, Plod1 antibody, PLOD3 antibody, plod1.L antibody, plod1a antibody

Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID: 5351

UniProt: Q02809