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NUP214 antibody

NUP214 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7264387
  • Target See all NUP214 Antibodies
    NUP214 (Nucleoporin 214kDa (NUP214))
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUP214 antibody is un-conjugated
    Application
    • 11
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human NUP214 (NP_005076.3).
    Isotype
    IgG
    Top Product
    Discover our top product NUP214 Primary Antibody
  • Application Notes
    IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NUP214 (Nucleoporin 214kDa (NUP214))
    Alternative Name
    NUP214 (NUP214 Products)
    Synonyms
    CAN antibody, CAN/Nup214 antibody, CG3820 antibody, DCAN antibody, DNup214 antibody, Dmel\\CG3820 antibody, Nup 214 antibody, dCAN antibody, l(2)10444 antibody, nup214 antibody, NUP214 antibody, RGD1304977 antibody, BC039282 antibody, D2H9S46E antibody, CAIN antibody, D9S46E antibody, N214 antibody, p250 antibody, Nucleoporin 214kD antibody, nucleoporin 214kDa antibody, nucleoporin 214 antibody, Nup214 antibody, NUP214 antibody
    Background
    The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
    Gene ID
    8021
    UniProt
    P35658
    Pathways
    Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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