NUP214 antibody (AA 230-310)

Catalog No. ABIN7230162

The Rabbit Polyclonal anti-NUP214 antibody (ABIN7230162) specifically detects NUP214 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for NUP214 antibody (AA 230-310) (ABIN7230162)

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP214 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUP214 Antibody

Binding Specificity: AA 230-310

Purpose: Rabbit Anti-NU214 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of NU214 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NU214 protein at AA range: 230-310

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for NUP214

Target: NUP214 (Nucleoporin 214kDa (NUP214))

Alternative Name: NU214

Background: Nuclear pore complex protein Nup214, 214 kDa nucleoporin, Nucleoporin Nup214, Protein CANNUP214 (Nucleoporin 214) is a member of the FG-repeat-containing nucleoporins. The protein encoded by NUP214 is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of NUP214 forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome.

Molecular Weight: 229kD

Gene ID: 8021

UniProt: P35658

Pathways: Protein targeting to Nucleus, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection