PTPN18 antibody
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- Target See all PTPN18 Antibodies
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PTPN18 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human PTPN18 (NP_001135842.1).
- Isotype
- IgG
- Top Product
- Discover our top product PTPN18 Primary Antibody
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- Application Notes
- WB 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PTPN18 (Protein tyrosine Phosphatase, Non-Receptor Type 18 (Brain-Derived) (PTPN18))
- Alternative Name
- PTPN18 (PTPN18 Products)
- Synonyms
- BDP1 antibody, PTP-HSCF antibody, FLP1 antibody, HSCF antibody, PTP-K1 antibody, Ptpk1 antibody, PTP20 antibody, protein tyrosine phosphatase, non-receptor type 18 antibody, PTPN18 antibody, Ptpn18 antibody
- Background
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
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Observed_MW: 60 kDa
Calculated_MW: 38 kDa/50 kDa
- Gene ID
- 26469
- UniProt
- Q99952
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