POLD4 antibody

Catalog No. ABIN7264557

The Rabbit Polyclonal anti-POLD4 antibody has been validated for WB. It is suitable to detect POLD4 in samples from Human.

Quick Overview for POLD4 antibody (ABIN7264557)

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLD4 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human POLD4 (NP_066996.3).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLD4

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Alternative Name: POLD4

Background: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight:

Observed_MW: 20 kDa

Calculated_MW: 8 kDa/12 kDa

Gene ID: 57804

UniProt: Q9HCU8

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA