POLD4 antibody

Catalog No. ABIN7228276

The Rabbit Polyclonal anti-POLD4 antibody is suitable to detect POLD4 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for POLD4 antibody (ABIN7228276)

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLD4 Antibody

Purpose: Rabbit Anti-DPOD4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DPOD4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DPOD4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLD4

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Alternative Name: DPOD4

Background: DNA polymerase delta subunit 4, DNA polymerase delta subunit p12POLD4 (DNA Polymerase Delta 4, Accessory Subunit) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Telomere C-strand (Lagging Strand) Synthesis. POLD4 encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein.

Molecular Weight: 11kD

Gene ID: 57804

UniProt: Q9HCU8

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA