Lamin A/C antibody (C-Term)

Catalog No. ABIN7013880

This Goat Polyclonal antibody specifically detects Lamin A/C in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Lamin A/C antibody (C-Term) (ABIN7013880)

Target: Lamin A/C (LMNA)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Grade: Verified

Product Details anti-Lamin A/C Antibody

Binding Specificity: C-Term

Purpose: Lamin A / Lamin A/C

Sequence: PRTQSPQNCS IM

Specificity: This antibody is expected to recognise isoforms 1 and 3 (NP_733821.1, NP_733822.1).

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Prostate. Recommended concentration: 5 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA

Background: LMNA, FPL, LFP, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, PRO1, CMD1A, CMT2B1, LGMD1B, lamin A, lamin A\/C, lamin A/C, 70 kDa lamin, progeria 1 (Hutchinson-Gilford type), Charcot-Marie-Tooth disease, axonal, type 2B1

Gene ID: 4000

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus