WNK1 antibody (AA 1601-1750) (FITC)

Catalog No. ABIN701477

Product Details anti-WNK1 Antibody (FITC)

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Binding Specificity: AA 1601-1750

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WNK1 antibody is conjugated to FITC

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human WNK1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for WNK1

Target: WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

Alternative Name: WNK1 (WNK1 Products)

Synonyms: HSAN2 antibody, HSN2 antibody, KDP antibody, PRKWNK1 antibody, PSK antibody, p65 antibody, WNK1 antibody, kdp antibody, psk antibody, hsn2 antibody, hsan2 antibody, pha2c antibody, prkwnk1 antibody, 6430573H23Rik antibody, EG406236 antibody, Hsn2 antibody, Prkwnk1 antibody, mKIAA0344 antibody, ATWNK1 antibody, T9J14.14 antibody, T9J14_14 antibody, ZIK4 antibody, with no lysine (K) kinase 1 antibody, WNK lysine deficient protein kinase 1 antibody, WNK lysine deficient protein kinase 1 L homeolog antibody, serine/threonine-protein kinase WNK1 antibody, with no lysine (K) kinase 1 antibody, WNK1 antibody, wnk1.L antibody, wnk1 antibody, LOC100056745 antibody, Wnk1 antibody

Background:

Synonyms: Erythrocyte 65 kDa protein, HSAN2, HSN2, hWNK1, KDP, KIAA0344, Kinase deficient protein, MGC163339, MGC163341, p65, PRKWNK1, Prostate derived sterile 20 like kinase, Protein kinase lysine deficient 1, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, PSK, Serine/threonine protein kinase WNK1, Serine/threonine-protein kinase WNK1, With no K, WNK lysine deficient protein kinase 1, WNK1, WNK1_HUMAN.

Background: WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.

Gene ID: 65125