SCN3A antibody (3rd Extracellular Loop, Domain 1)
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- Target See all SCN3A Antibodies
- SCN3A (Sodium Channel, Voltage-Gated, Type III, alpha Subunit (SCN3A))
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Binding Specificity
- 3rd Extracellular Loop, AA 277-288, Domain 1
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCN3A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Live Cell Imaging (LCI)
- Cross-Reactivity (Details)
- May recognize NaV1.1 and NaV1.2 due to a moderate homology between the chosen sequence and the sequences of NaV1.1 and NaV1.2 (although there are no five amino acids identical in a row as considered to be the minimum needed for antibody/antigen recognition).
- Characteristics
- Anti-SCN3A (Nav1.3) (extracellular) Antibody is directed against an epitope of the rat NaV1.3 channel. Anti-SCN3A (NaV1.3) (extracellular) Antibody (ABIN7043644, ABIN7045250 and ABIN7045251)) can be used in western blot, and live cell imaging applications. It has been designed to recognize NaV1.3 from rat, human and mouse samples. The antibody may recognize NaV1.1 and NaV1.2 due to a moderate homology between the chosen sequence and the sequences of NaV1.1 and NaV1.2 (although there are no five amino acids identical in a row as considered to be the minimum needed for antibody/antigen recognition).
- Purification
- Affinity purified on immobilized antigen.
- Immunogen
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Immunogen: Synthetic peptide
Immunogen Sequence: CSQWPPSDSAFE, corresponding to amino acid residues 277-288 of rat NaV1.3
- Isotype
- IgG
- Top Product
- Discover our top product SCN3A Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
- Concentration
- 0.85 mg/mL
- Buffer
- Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- RT,4 °C,-20 °C
- Storage Comment
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Target
- SCN3A (Sodium Channel, Voltage-Gated, Type III, alpha Subunit (SCN3A))
- Alternative Name
- SCN3A (NaV1.3) (SCN3A Products)
- Synonyms
- SCN3A antibody, nav1.3 antibody, Gm1000 antibody, Nav1.3 antibody, SCIII antibody, Scn2a antibody, NAC3 antibody, sodium voltage-gated channel alpha subunit 3 antibody, sodium channel, voltage gated, type III alpha subunit antibody, sodium channel protein type 9 subunit alpha antibody, sodium channel, voltage-gated, type III, alpha antibody, sodium channel protein type 3 subunit alpha antibody, SCN3A antibody, scn3a antibody, LOC100180733 antibody, Scn3a antibody, LOC534223 antibody
- Background
- Alternative names: SCN3A (NaV1.3), BIII, Brain type III Na+ channel, Sodium channel protein type 3 subunit alpha
- Gene ID
- 497770
- NCBI Accession
- NM_006922
- UniProt
- P08104
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