Recombinant ErbB2/Her2 antibody (Extracellular Domain)
Quick Overview for Recombinant ErbB2/Her2 antibody (Extracellular Domain) (ABIN7072299)
Target
See all ErbB2/Her2 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- Extracellular Domain
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Purpose
- Anti-HER2/neu [SER4], Mouse IgG1, kappa
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Specificity
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The antibody binds specifically to the extracellular domain of human ErbB-2.
Application Notes original Clone: The antibody binds to human ErbB-2, a receptor tyrosine kinase (RTK) controlling cell growth and microtubule stabilization. Full-length antibody or Fab fragments cross-linked by secondary antibody had a growth-inhibiting effect onf ErbB-2 positive MDA-MB-453 cells. This effect was not seen with Fab fragments alone.
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Purification
- Protein A affinity purified
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Immunogen
- Recombinant HER2/neu.
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Isotype
- IgG1, kappa
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anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 23-372) antibody
ErbB2/Her2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reactivity: Human, Mouse, Rat, Dog, Monkey, Horse, Pig, Cow, Rabbit, Hamster, Avian, Cat, Chicken, Donkey, Goat, Guinea Pig, Sheep WB, IHC (p), IHC (fro) Host: Goat Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 22-121) antibodyErbB2/Her2 Reactivity: Human IF, ELISA, IHC (p), PLA Host: Mouse Monoclonal 3B1 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivity: Human IHC, IF, FACS Host: Mouse Monoclonal ERBB2-2452 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 311-462) antibodyErbB2/Her2 Reactivity: Human IHC Host: Mouse Monoclonal ERBB2-3078 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (AA 1205-1255) antibodyErbB2/Her2 Reactivity: Human, Mouse WB, IHC, FACS, IP, ICC Host: Rabbit Monoclonal BLR241L unconjugated Recombinant Antibody
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (N-Term) antibodyErbB2/Her2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (Extracellular Domain) antibodyErbB2/Her2 Reactivity: Human IF, ELISA, FACS Host: Mouse Monoclonal HRB2-282 unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (C-Term) antibodyErbB2/Her2 Reactivity: Human IHC, IF (p) Host: Rabbit Polyclonal unconjugated
anti-Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2) (pTyr1196) antibodyErbB2/Her2 Reactivity: Human WB, IF, DB Host: Rabbit Polyclonal RB40085 unconjugated
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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Alternative Name
- HER2/neu
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Background
- ERBB2, Receptor tyrosine-protein kinase erbB-2, human epidermal growth factor receptor 2,
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UniProt
- P04626
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Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
Target
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