CLEC2D antibody

Catalog No. ABIN7073248

Product Details anti-CLEC2D Antibody

Target: CLEC2D (C-Type Lectin Domain Family 2, Member D (CLEC2D))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC2D antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse CLEC2D

Application Details

Application Notes: WB (R) 1:500- 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CLEC2D

Target: CLEC2D (C-Type Lectin Domain Family 2, Member D (CLEC2D))

Alternative Name: CLEC2D (CLEC2D Products)

Synonyms: CLAX antibody, LLT1 antibody, OCIL antibody, Clr-b antibody, Clrb antibody, Ocil antibody, Clec2d5 antibody, CLEC2D antibody, C-type lectin domain family 2 member D antibody, C-type lectin domain family 2, member d antibody, C-type lectin domain family 2, member D antibody, CLEC2D antibody, Clec2d antibody

Background: CLEC2D (C-type lectin domain family 2 member D), also known as LLT1 (lectin-like transcript 1) or OCIL (Osteoclast inhibitory lectin), is a single-pass type II membrane protein expressed by hematopoietic cells and osteoblasts . Its expression was found to be tightly correlated with activation on T cells, NK cells, B cells, and DCs . CLEC2D is a ligand for the human NKR-P1A (CD161) receptor and that their interaction differentially regulates NK- and T-cell functions . It inhibits the formation and function of osteoclasts and modulates the release of interferon-gamma by human NK cells.

Molecular Weight: 24 kDa

Gene ID: 93694

NCBI Accession: NP_444339

UniProt: Q91V08

Pathways: Regulation of Leukocyte Mediated Immunity