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FBXW4 antibody

FBXW4 Reactivity: Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7073903
  • Target See all FBXW4 Antibodies
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Reactivity
    • 33
    • 12
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Mouse, Rat
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    This FBXW4 antibody is un-conjugated
    Application
    • 29
    • 28
    • 9
    • 4
    • 3
    • 3
    Western Blotting (WB)
    Cross-Reactivity
    Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse FBXW4
    Top Product
    Discover our top product FBXW4 Primary Antibody
  • Application Notes
    WB (M,R) 1:1000-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    Alternative Name
    FBXW4 (FBXW4 Products)
    Synonyms
    dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
    Background
    F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
    Molecular Weight
    46 kDa
    Gene ID
    30838
    NCBI Accession
    NP_038935
    UniProt
    Q9JMJ2
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