FBXW4 antibody
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- Target See all FBXW4 Antibodies
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This FBXW4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Rat
- Purification
- Affinity purification
- Immunogen
- Recombinant protein corresponding to Mouse FBXW4
- Top Product
- Discover our top product FBXW4 Primary Antibody
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- Application Notes
- WB (M,R) 1:1000-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
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- Target
- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
- Alternative Name
- FBXW4 (FBXW4 Products)
- Synonyms
- dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
- Background
- F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
- Molecular Weight
- 46 kDa
- Gene ID
- 30838
- NCBI Accession
- NP_038935
- UniProt
- Q9JMJ2
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