LAT2 antibody
Quick Overview for LAT2 antibody (ABIN7074503)
Target
See all LAT2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Cross-Reactivity
- Rat
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse LAT2
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Application Notes
- IHC/IF (M,R) 1:300-1:600
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))
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Alternative Name
- LAT2
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Background
- L-amino acid transporter protein-2 (LAT2), a non-glycosylated membrane protein, complexes with CD98 to contribute to readsorption of neutral amino acids in renal epithelia and blood-tissue barriers. The gene encoding LAT2 is expressed primarily in the kidney, but also to a lesser extent in placenta, brain, liver, spleen, skeletal muscle, heart, small intestine, and lung. Transfection with the antisense sequence of LAT2 suggests that LAT2 expression plays a major role in net basolateral efflux of cysteine, and points to LAT2 as a candidate gene to modulate cysteine reabsorption.
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Gene ID
- 50934
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UniProt
- Q9QXW9
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Pathways
- Fc-epsilon Receptor Signaling Pathway, BCR Signaling
Target
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