Nectin-1 (NECTIN1) antibody

Catalog No. ABIN7074789

Product Details

Target: Nectin-1 (NECTIN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse PVRL1/NECTIN1

Application Details

Application Notes: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details

Target: Nectin-1 (NECTIN1)

Alternative Name: PVRL1/NECTIN1

Synonyms: CD111 antibody, CLPED1 antibody, ED4 antibody, HIgR antibody, HVEC antibody, OFC7 antibody, PRR antibody, PRR1 antibody, PVRR antibody, PVRR1 antibody, SK-12 antibody, nectin-1 antibody, nectin cell adhesion molecule 1 antibody, NECTIN1 antibody

Background: This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate.

Molecular Weight: 57 kDa

Gene ID: 58235

NCBI Accession: NP_067399

UniProt: Q9JKF6