NFASC antibody

Catalog No. ABIN7074812

Product Details anti-NFASC Antibody

Target: NFASC (Neurofascin (NFASC))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFASC antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Neurofascin

Application Details

Application Notes: WB (M,R) 1: 500-1: 1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for NFASC

Target: NFASC (Neurofascin (NFASC))

Alternative Name: Neurofascin (NFASC Products)

Synonyms: sc:d0205 antibody, NF antibody, NRCAML antibody, AA387016 antibody, D430023G06Rik antibody, mKIAA0756 antibody, neurofascin antibody, neurofascin homolog (chicken) a antibody, NFASC antibody, nfasca antibody, Nfasc antibody

Background: Neurofascin encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin.

Molecular Weight: 186 kDa

Gene ID: 269116

NCBI Accession: NP_874385

UniProt: Q810U3

Pathways: Cell-Cell Junction Organization