POLD4 antibody

Catalog No. ABIN7075131

The Rabbit Polyclonal anti-POLD4 antibody is suitable to detect POLD4 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for POLD4 antibody (ABIN7075131)

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLD4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POLD4 Antibody

Cross-Reactivity: Human, Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse POLD4

Application Details

Application Notes: WB (H,M,R) 1:500- 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for POLD4

Target: POLD4 (Polymerase (DNA-Directed), delta 4, Accessory Subunit (POLD4))

Alternative Name: POLD4

Background: This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 18 kDa

Gene ID: 69745

NCBI Accession: NP_081472

UniProt: Q9CWP8

Pathways: Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA