PKA antibody (Catalytic Subunit)
Quick Overview for PKA antibody (Catalytic Subunit) (ABIN7075244)
Target
See all PKA AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Catalytic Subunit
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Cross-Reactivity
- Human, Rat
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Purification
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse PKA alpha+beta
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Application Notes
- WB (H,M,R) 1: 500-1: 1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- PKA (Protein Kinase A (PKA))
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Alternative Name
- PKA alpha+beta
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Background
- The catalytic subunit α of protein kinase A is a key regulatory enzyme that in humans is encoded by the PRKACA gene. This enzyme is responsible for phosphorylating other proteins and substrates, changing their activity. Protein kinase A catalytic subunit (PKA Cα) is a member of the AGC kinase family (protein kinases A, G, and C), and contributes to the control of cellular processes that include glucose metabolism, cell division, and contextual memory. PKA Cα is part of a larger protein complex that is responsible for controlling when and where proteins are phosphorylated. Defective regulation of PKA holoenzyme activity has been linked to the progression of cardiovascular disease, certain endocrine disorders and cancers.
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Molecular Weight
- 41 kDa
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Gene ID
- 18747
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NCBI Accession
- NP_001264827
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UniProt
- P05132
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Pathways
- SARS-CoV-2 Protein Interactome
Target
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