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SUPT3H/SPT3 antibody

SUPT3H Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7075767
  • Target See all SUPT3H/SPT3 (SUPT3H) Antibodies
    SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))
    Reactivity
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SUPT3H/SPT3 antibody is un-conjugated
    Application
    • 16
    • 13
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Cross-Reactivity
    Mouse, Rat
    Purification
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Human SUPT3H
  • Application Notes
    WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:500-1:1500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    SUPT3H/SPT3 (SUPT3H) (Suppressor of Ty 3 Homolog (SUPT3H))
    Alternative Name
    SUPT3H (SUPT3H Products)
    Synonyms
    SPT3 antibody, SPT3L antibody, supt3h antibody, MGC75923 antibody, zgc:92246 antibody, SUPT3H antibody, SPT3 homolog, SAGA and STAGA complex component antibody, SPT3 homolog, SAGA and STAGA complex component L homeolog antibody, SUPT3H antibody, supt3h antibody, supt3h.L antibody, Supt3h antibody
    Background
    The transcription of many RNA polymerase II-dependent genes requires Spt3, a member of the S. cerevisiae SAGA complex. Transcription from delta sequences, the long terminal repeats that flank yeast Ty elements, requires the yeast SPT3 gene. Spt3 and Spt20 work together to recruit TATA-box binding protein (TBP) to the core promoter allowing TBP to bind to SAGA-dependent promoters. Null mutations in the Spt3 gene cause defects in sporulation, diploid filamentous growth, and haploid invasive growth, indicating that Spt3 has an important role in both mating and development pathways in yeast. At the promoters of some genes including yeast HO, HIS3 and TRP3 genes, Spt3 inhibits binding of TBP, resulting in reduced transcription.
    Molecular Weight
    36 kDa
    Gene ID
    8464
    UniProt
    O75486
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