SYNM antibody

Catalog No. ABIN7075800

Product Details anti-SYNM Antibody

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNM antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Desmuslin/SYN

Application Details

Application Notes: IHC/IF (M,R) 1:500-1:1000/1:500-1:1300

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SYNM

Target: SYNM (Synemin, Intermediate Filament Protein (SYNM))

Alternative Name: Desmuslin/SYN (SYNM Products)

Synonyms: DMN antibody, dmn antibody, si:dkey-25f3.3 antibody, SYN antibody, 4930412K21Rik antibody, AI852401 antibody, Dmn antibody, E130104F11 antibody, Syn antibody, Synemin antibody, synemin antibody, synemin, intermediate filament protein antibody, SYNM antibody, synm antibody, Synm antibody

Background: SYNM, also named as DMN, KIAA0353 and SYN, belongs to the intermediate filament family. SYNM is a Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.

Gene ID: 233335

NCBI Accession: NP_705819

UniProt: Q8BGV0