TINF2 antibody

Catalog No. ABIN7075860

Product Details anti-TINF2 Antibody

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TINF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse Tin2

Application Details

Application Notes: WB (M,R) 1:500-1:1000, IHC/IF (R) 1:3800-1:7600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Alternative Name: Tin2 (TIN2 Products)

Synonyms: DKCA3 antibody, TIN2 antibody, AW552114 antibody, D14Wsu146e antibody, Tin2 antibody, TERF1 interacting nuclear factor 2 antibody, Terf1 (TRF1)-interacting nuclear factor 2 antibody, TINF2 antibody, Tinf2 antibody

Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly.

UniProt: Q9QXG9

Pathways: Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process