TINF2 antibody (AA 210-451)

Catalog No. ABIN7171778

Product Details anti-TINF2 Antibody

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Binding Specificity: AA 210-451

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TINF2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TERF1-interacting nuclear factor 2 protein (210-451AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Alternative Name: TINF2 (TIN2 Products)

Synonyms: DKCA3 antibody, TIN2 antibody, AW552114 antibody, D14Wsu146e antibody, Tin2 antibody, TERF1 interacting nuclear factor 2 antibody, Terf1 (TRF1)-interacting nuclear factor 2 antibody, TINF2 antibody, Tinf2 antibody

Background:

Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Aliases: AW552114 antibody, D14Wsu146e antibody, DKCA3 antibody, MGC94711 antibody, TERF 1 (TRF 1) interacting nuclear factor 2 antibody, TERF 1 interacting nuclear factor 2 antibody, TERF1 (TRF1) interacting nuclear factor 2 antibody, TERF1 interacting nuclear factor 2 antibody, TERF1-interacting nuclear factor 2 antibody, Tin 2 antibody, TIN2 antibody, TINF 2 antibody, Tinf2 antibody, TINF2_HUMAN antibody, TRF 1 interacting nuclear factor 2 antibody, TRF1 interacting nuclear factor 2 antibody, TRF1-interacting nuclear protein 2 antibody

UniProt: Q9BSI4

Pathways: Cell Division Cycle, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process