TOR1AIP2 antibody

Catalog No. ABIN7075941

Product Details anti-TOR1AIP2 Antibody

Target: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOR1AIP2 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TOR1AIP2

Application Details

Application Notes: WB (M,R) 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TOR1AIP2

Target: TOR1AIP2 (Torsin A Interacting Protein 2 (TOR1AIP2))

Alternative Name: TOR1AIP2 (TOR1AIP2 Products)

Synonyms: IFRG15 antibody, LULL1 antibody, NET9 antibody, RP11-12M5.5 antibody, 1110020D10Rik antibody, 15kDa antibody, A130072J07 antibody, AA103493 antibody, AW060462 antibody, AW610675 antibody, C77739 antibody, Ifrg15 antibody, Lull1 antibody, torsin 1A interacting protein 2 antibody, torsin-1A-interacting protein 2 antibody, torsin A interacting protein 2 antibody, torsin-1A-interacting protein 2, isoform IFRG15 antibody, TOR1AIP2 antibody, LOC610310 antibody, LOC100050862 antibody, LOC100338750 antibody, LOC100385418 antibody, LOC100595243 antibody, Tor1aip2 antibody

Background: LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.

Molecular Weight: 58 kDa

Gene ID: 240832

NCBI Accession: NP_001153652

UniProt: Q9ER81