TCOF1 antibody

Catalog No. ABIN7076003

Product Details anti-TCOF1 Antibody

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCOF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Rat

Purification: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TCOF1

Application Details

Application Notes: IHC/IF (M,R) 1:1400-1:2800/1:700-1:1400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TCOF1

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: TCOF1 (TCOF1 Products)

Synonyms: TCOF1 antibody, AA408847 antibody, AW209012 antibody, treacle antibody, MFD1 antibody, TCS1 antibody, treacle ribosome biogenesis factor 1 antibody, Tcof1 antibody, TCOF1 antibody

Background: Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with NOLC1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.

Gene ID: 21453

NCBI Accession: NP_035682

UniProt: O08784