SORD antibody (AA 251-357) (Cy5.5)

Catalog No. ABIN704731

Product Details anti-SORD Antibody (Cy5.5)

Target: SORD (Sorbitol Dehydrogenase (SORD))

Binding Specificity: AA 251-357

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SORD antibody is conjugated to Cy5.5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Sorbitol Dehydrogenase

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SORD

Target: SORD (Sorbitol Dehydrogenase (SORD))

Alternative Name: SDH/Sorbitol Dehydrogenase (SORD Products)

Synonyms: SORD1 antibody, Sdh-1 antibody, Sdh1 antibody, Sodh-1 antibody, SDH antibody, sord antibody, MGC83437 antibody, BmSDH antibody, PSPTO0363 antibody, SODH-1 antibody, RATSDHE1 antibody, SDH2 antibody, Sdh antibody, Sdhe1 antibody, TDH antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SDS antibody, zgc:63674 antibody, sorbitol dehydrogenase antibody, sorbitol dehydrogenase L homeolog antibody, Sorbitol dehydrogenase antibody, serine dehydratase antibody, SBDS ribosome maturation factor antibody, SORD antibody, Sord antibody, sord.L antibody, sord antibody, Sdh antibody, LOC733025 antibody, polS antibody, RS_RS10765 antibody, sdh antibody, smoS antibody, Rsph17029_1731 antibody, Srd antibody, RSKD131_1411 antibody, SDS antibody, Sds antibody, Sbds antibody

Background:

Synonyms: L iditol 2 dehydrogenase, SDH, SORD 1, SORD, SORD1. DHSO_HUMAN

Background: Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme. SDH is expressed almost ubiquitously in all mammalian tissues. The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states. Although SORD is closely related to the class I long-chain alcohol dehydrogenases, it differs in substrate specificity, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols.

Gene ID: 6390