CD45RO antibody (mFluor™450)

Catalog No. ABIN7077264

Product Details anti-CD45RO Antibody (mFluor™450)

Target: CD45RO

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RO antibody is conjugated to mFluor™450

Application: Flow Cytometry (FACS)

Characteristics: The clone UCHL1 recognizes 180-185 KD surface antigen known as CD45RO commonly expressed by thymocytes, a subset of resting, memory and activated T cells, activated monocytes/macrophages, granulocytes and myeloma cells. CD45RO is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. It plays important rule in development of lymphocytes and antigen signaling, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: IL-2 dependent T cell line, CA-1

Clone: UCHL1

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD45RO

Target: CD45RO

Alternative Name: CD45RO (CD45RO Products)

Background: The clone UCHL1 recognizes 180-185 KD surface antigen known as CD45RO commonly expressed by thymocytes, a subset of resting, memory and activated T cells, activated monocytes/macrophages, granulocytes and myeloma cells. CD45RO is the shortest isoform of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. It plays important rule in development of lymphocytes and antigen signaling, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis.

Gene ID: 5788

UniProt: P08575