MRPL39 antibody (AA 151-250) (HRP)

Catalog No. ABIN704825

Product Details anti-MRPL39 Antibody (HRP)

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL39 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MrpL-39

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MRPL39

Target: MRPL39 (Mitochondrial Ribosomal Protein L39 (MRPL39))

Alternative Name: MrpL39 (MRPL39 Products)

Synonyms: CG17166 antibody, Dmel\\CG17166 antibody, MRP-L5 antibody, mRpL5 antibody, C21orf92 antibody, L39mt antibody, MRPL5 antibody, PRED22 antibody, PRED66 antibody, RPML5 antibody, C21orf8 antibody, ORF22 antibody, Rpml5 antibody, mitochondrial ribosomal protein L39 antibody, mitochondrial ribosomal protein L39 L homeolog antibody, mRpL39 antibody, mrpl39.L antibody, MRPL39 antibody, Mrpl39 antibody

Background:

Synonyms: L39mt, Mitochondrial ribosomal protein L39, MRP L5, MRPL5, MSTP003, PRED22, PRED66, RPML5, RM39_HUMAN.

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.

Gene ID: 54148