TBL1Y antibody (AA 501-577)

Catalog No. ABIN705416

Product Details anti-TBL1Y Antibody

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Binding Specificity: AA 501-577

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBL1Y antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: 100 % sequence similarity with TBL1Y

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TBL1X

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TBL1Y

Target: TBL1Y (Transducin (Beta)-Like 1, Y-Linked (TBL1Y))

Alternative Name: TBL1 (TBL1Y Products)

Synonyms: TBL1 antibody, transducin beta like 1, Y-linked antibody, TBL1Y antibody

Background:

Synonyms: TBL1, EBI, F box like/WD repeat protein TBL1X, SMAP 55, SMAP55, TBL 1, TBL1X, Transducin beta like 1, Transducin beta like 1 X linked, Transducin beta like 1 X linked, Transducin beta like 1X, Transducin beta like 1X protein, TBL1X_HUMAN, F-box-like/WD repeat-containing protein TBL1X, Full=Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked..

Background: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq].

Gene ID: 6907, 90665