Aurora A antibody (AA 41-140) (Biotin)

Catalog No. ABIN7090771

The Rabbit Polyclonal anti-Aurora A antibody has been validated for WB. It is suitable to detect Aurora A in samples from Mouse.

Quick Overview for Aurora A antibody (AA 41-140) (Biotin) (ABIN7090771)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora A antibody is conjugated to Biotin

Application: Western Blotting (WB)

Product Details anti-Aurora A Antibody (Biotin)

Binding Specificity: AA 41-140

Cross-Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Aurora A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: Aurora A

Background:

Synonyms: AIK, ARK-1, ARK1, AURA, AURKA, Aurora 2, Aurora Family Kinase 1, aurora kinase A, Aurora Related Kinase 1, Aurora-related kinase 1, Aurora/IPL1 Like Kinase, Aurora/IPL1 Related Kinase 1, Aurora/IPL1-related kinase 1, AURORA2, AYK1, BRAK, Breast Tumor Amplified Kinase, Breast tumor-amplified kinase, BTAK, hARK1, IAK, IPL1 Aurora Related Kinase 1, IPL1 Related Kinase, MGC34538, OTTHUMP00000031340, OTTHUMP00000031341, OTTHUMP00000031342, OTTHUMP00000031343, OTTHUMP00000031344, OTTHUMP00000031345, OTTHUMP00000166071, OTTHUMP00000166072, PPP1R47, Protein phosphatase 1, regulatory subunit 47, Serine/threonine kinase 15, Serine/threonine kinase 6, Serine/threonine kinase, Serine/threonine kinase, Serine/threonine-protein kinase 15, Serine/threonine-protein kinase 6, Serine/threonine-protein kinase aurora-A, STK15, STK6, AURKA_MOUSE, STK7.

Background: Phosphorylates numerous target proteins, including ARHGEF2, BRCA1, KIF2A, NDEL1, PARD3, PLK1 and BORA. Regulates KIF2A tubulin depolymerase activity. Required for normal axon formation. Plays a role in microtubule remodeling during neurite extension. Important for microtubule formation and/or stabilization.

Gene ID: 20878

UniProt: P97477

Pathways: Cell Division Cycle, Asymmetric Protein Localization