CAMK2B antibody (AA 1-503)

Catalog No. ABIN7090800

This Mouse Monoclonal antibody specifically detects CAMK2B in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CAMK2B antibody (AA 1-503) (ABIN7090800)

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CAMK2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: F4A2

Product Details anti-CAMK2B Antibody

Binding Specificity: AA 1-503

Predicted Reactivity: Human,Mouse,Rat

Immunogen: Recombinant human CAMK2 between 1-503 amino acids.

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CAMK2B

Target: CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))

Alternative Name: CAMK2 beta

Background:

Synonyms: Calcium/calmodulin dependent protein kinase (CaM kinase) II beta, Calcium/calmodulin dependent protein kinase II beta, Calcium/calmodulin dependent protein kinase IIB, Calcium/calmodulin dependent protein kinase type II beta chain, calcium/calmodulin-dependent protein kinase II beta, Calcium/calmodulin-dependent protein kinase type II subunit beta, CAM 2, CaM kinase II beta chain, CaM kinase II beta subunit, CaM kinase II subunit beta, CaM-kinase II beta chain, CAM2, CAMK 2, CAMK 2B, CaMK II beta subunit, CaMK II subunit beta, CaMK-II subunit beta, CAMK2, Camk2b, CAMKB, CaMKII beta subunit, CaMKIIB, KCC2B_HUMAN, MGC29528, Proline rich calmodulin dependent protein kinase, proline rich calmodulin-dependent protein kinase,

Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplamic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

Gene ID: 816

UniProt: Q13554

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity