Integrin Alpha2b antibody

Catalog No. ABIN7091262

This Mouse Monoclonal antibody specifically detects Integrin Alpha2b in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for Integrin Alpha2b antibody (ABIN7091262)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 9B10

Product Details anti-Integrin Alpha2b Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CD41/Integrin alpha 2b

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M PBS( pH 7.4) with 0.1 % Proclin300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41/Integrin alpha 2b

Background:

Synonyms: platelet glycoprotein IIb of IIb/IIIa complex, Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), ITGA2B, GPIIb, GTA, HPA3, CD 41, CD41, CD41 antigen, CD41a, CD41b, GP2b, GPalpha IIb, GPalphaIIb, Integrin alpha IIb, Integrin alpha IIb precursor, ITGA 2B, ITGA2B, ITGAB, Platelet fibrinogen receptor alpha, Platelet fibrinogen receptor alpha subunit, Platelet glycoprotein IIb of IIb/IIIa complex, Platelet membrane glycoprotein IIb, Platelet specific antigen bak, ITA2B_HUMAN.

Background: Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex