ITGA5 antibody (AA 981-1049)

Catalog No. ABIN7091269

Product Details anti-ITGA5 Antibody

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Binding Specificity: AA 981-1049

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin alpha 5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: Integrin alpha 5 (ITGA5 Products)

Synonyms: ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody

Background:

Synonyms: Integrin alpha-5 light chain, Alpha 5 beta 1, CD49 antigen-like family member E, CD49e, ECMRVI, Fibronectin Receptor alpha, Fibronectin receptor alpha subunit, Fibronectin receptor, alpha subunit, FNR, FNRA, gpIc/IIa, Integrin alpha 5 (fibronectin receptor alpha), Integrin alpha 5, Integrin alpha F, Integrin alpha-5, Integrin alpha-F, Integrin, alpha 5 (fibronectin receptor, alpha polypeptide), ITGA5, Very late Activation Antigen 5, Very Late Activation Protein 5 alpha, Very late activation protein 5, alpha subunit, VLA5, VLA5A, ITA5_HUMAN, Integrin α5, Integrin-α5.

Background: CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5), in platelets as glycoprotein IcIIa, and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling.

Gene ID: 3678

UniProt: P08648

Pathways: Integrin Complex