SPI1 antibody

Catalog No. ABIN7091693

The Mouse Monoclonal anti-SPI1 antibody (Clone K8J9) (ABIN7091693) specifically detects SPI1 in WB. The antibody is reactive with Human samples.

Quick Overview for SPI1 antibody (ABIN7091693)

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SPI1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: K8J9

Product Details anti-SPI1 Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human SPI1.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SPI1

Target: SPI1 (Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1 (SPI1))

Alternative Name: PU.1/Spi1

Background:

Synonyms: 31 kDa Transforming Protein, 31 kDa-transforming protein, Hematopoietic transcription factor PU.1, OF, SFPI1, SPI 1 proto oncogene, SPI A, SPI1_HUMAN, Spleen focus forming virus (SFFV) proviral integration oncogene spi1, Transcription factor PU.1.

Background: Binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. This protein is a transcriptional activator that may be specifically involved in the differentiation or activation of macrophages or B-cells. Also binds RNA and may modulate pre-mRNA splicing.

Gene ID: 6688

UniProt: P17947

Pathways: Stem Cell Maintenance