SWAP70 antibody

Catalog No. ABIN7091710

The Mouse Monoclonal anti-SWAP70 antibody is suitable to detect SWAP70 in samples from Human. It has been validated for WB.

Quick Overview for SWAP70 antibody (ABIN7091710)

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SWAP70 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: M11F7

Product Details anti-SWAP70 Antibody

Predicted Reactivity: Human

Immunogen: Recombinant human SWAP70 (Fragment) (His-tagged).

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SWAP70

Target: SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))

Alternative Name: SWAP70

Background:

Synonyms: KIAA0640, 70 kDa, AV235546, FLJ39540, HSPC321, SWA 70 protein, SWAP 70, SWAP switching B-cell complex 70 kDa subunit, SWAP-70, Switch associated protein 70, Switch-associated protein 70, SWP70_HUMAN.

Background: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.

Gene ID: 23075

UniProt: Q9UH65

Pathways: Production of Molecular Mediator of Immune Response