Girdin antibody (pSer1765)
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- Target See all Girdin (CCDC88A) Antibodies
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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Binding Specificity
- pSer1765
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Girdin antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- Human,Mouse,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthesised phosphopeptide derived from human APE around the phosphorylation site of Ser1765
- Clone
- G5F7
- Isotype
- IgG
- Top Product
- Discover our top product CCDC88A Primary Antibody
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- Application Notes
- IHC-P 1:200-400
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
- Alternative Name
- Girdin (CCDC88A Products)
- Synonyms
- APE antibody, GIRDIN antibody, GIV antibody, GRDN antibody, HkRP1 antibody, KIAA1212 antibody, A430106J12Rik antibody, AI848406 antibody, Ape antibody, C130096N06Rik antibody, C330012F17Rik antibody, D130005J21Rik antibody, Girdin antibody, Giv antibody, Grdn antibody, Hkrp1 antibody, DKFZp459N1815 antibody, RGD1306694 antibody, coiled-coil domain containing 88A antibody, coiled coil domain containing 88A antibody, CCDC88A antibody, Ccdc88a antibody
- Background
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Synonyms: GIV (pY1765), Girdin (phospho Y1765), p-Girdin (phospho Y1765), Akt phosphorylation enhancer, APE, Coiled coil domain containing protein 88A, G alpha interacting vesicle associated protein, Girders of actin filament, GIV, HkRP1, Hook related protein 1, AKT iphosphorylation enhancer, Akt phosphorylation enhancer, Ccdc88a, GIV, GRDN, GRDN_HUMAN, HkRP1, Hook related protein 1, Hook-related protein 1, KIAA1212.
Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
- Gene ID
- 55704
- UniProt
- Q3V6T2
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