Histone H2B antibody (acLys20)

Catalog No. ABIN7091906

The Mouse Monoclonal anti-Histone H2B antibody (Clone H2F5) (ABIN7091906) specifically detects Histone H2B in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Histone H2B antibody (acLys20) (7091906)

Target: Histone H2B

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Histone H2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: H2F5

Product Details anti-Histone H2B Antibody

Binding Specificity: acLys20

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human Histone H2B (Acetyl K20)

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Histone H2B

Target: Histone H2B

Background:

Synonyms: H2BK20ac, Histone H2B (Acetyl Lys20), Acetyl Histone H2B (20), acetyl-Histone H2B (Lys20), Histone H2B/HIST1H2BD, H2B.1, H2B.1 B, H2B.b, H2B.c, H2B.d, H2B.e, H2B.f, H2B.j, H2B.q, H2BFB, H2BFC, H2BFD, H2BFE, H2BFF, H2BFJ, H2BFO, H2BFQ, H2BFS, HIRIP2, HIST1H2BB, HIST1H2BD, HIST1H2BH, HIST1H2BL, HIST1H2BM, HIST1H2BN, HIST2H2BE, Histone H2B, Histone H2B type 1 B, Histone H2B type 1 D, Histone H2B type 1 H, Histone H2B type 1 L, Histone H2B type 1 M, Histone H2B type 1 N, Histone H2B type 2 E, Histone protein, H2B GL105, H2B histone family member O, H2B histone family member S, histone H2B type 1-B, H2B1B_HUMAN.

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008].

Gene ID: 3018

UniProt: P33778