CDH23 antibody
Quick Overview for CDH23 antibody (ABIN7112149)
Target
See all CDH23 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- CDH23 antibody
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- cadherin-like 23
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Isotype
- IgG
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Application Notes
- WB: 1:500 - 1:2000, IHC: 1:100 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months
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Expiry Date
- 12 months
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- CDH23 (Cadherin 23 (CDH23))
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Alternative Name
- CDH23
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Background
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Synonyms: Cadherin-23|Otocadherin|CDH23|KIAA1774|KIAA1812
Background: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.
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Molecular Weight
- 59 kDa
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Gene ID
- 64072
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UniProt
- Q9H251
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Pathways
- Sensory Perception of Sound
Target
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