ERCC6L antibody

Catalog No. ABIN7113991

This Rabbit Polyclonal antibody specifically detects ERCC6L in ELISA and WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ERCC6L antibody (ABIN7113991)

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC6L antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ERCC6L Antibody

Purpose: ERCC6L antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: excision repair cross-complementing rodent repair deficiency, complementation group 6-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ERCC6L

Target: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Alternative Name: ERCC6L

Background:

Synonyms: DNA excision repair protein ERCC-6-like|ATP-dependent helicase ERCC6-like|PLK1-interacting checkpoint helicase|Tumor antigen BJ-HCC-15|ERCC6L|PICH

Background: DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase.

Molecular Weight: 180 kDa

Gene ID: 54821

UniProt: Q2NKX8