FAM3C antibody

Catalog No. ABIN7114092

Product Details anti-FAM3C Antibody

Target: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAM3C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: family with sequence similarity 3, member C

Clone: 2A10

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for FAM3C

Target: FAM3C (Family with Sequence Similarity 3, Member C (FAM3C))

Alternative Name: FAM3C (FAM3C Products)

Synonyms: ILEI antibody, D6Wsu176e antibody, Ilei antibody, wu:fb99h11 antibody, wu:fi35h03 antibody, zgc:55444 antibody, zgc:77090 antibody, family with sequence similarity 3 member C antibody, family with sequence similarity 3, member C antibody, family with sequence similarity 3 member C L homeolog antibody, fam3c antibody, FAM3C antibody, Fam3c antibody, fam3c.L antibody

Background: Synonyms:FAM3C, Protein FAM3C, GS3786, Interleukin like EMT inducer, ILEI Background:FAM3C, also known as ILEI, is a secreted protein belonging to the cytokine-like protein family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. A change in expression of this protein has been noted in pancreatic cancer-derived cells. FAM3C has been involved in the epithelial to mesenchymal transition, and retinal laminar formation processes in vertebrates. Also, FAM3C may play an important role in inner ear development and thus be involved in cell differentiation and proliferation during inner ear embryogenesis.

Molecular Weight: 25kd

Gene ID: 10447

UniProt: Q92520