IDS antibody
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- Target See all IDS Antibodies
- IDS (Iduronate 2-Sulfatase (IDS))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IDS antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Purification
- Protein A+G purification
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- iduronate 2-sulfatase
- Clone
- 2D2
- Isotype
- IgG1
- Top Product
- Discover our top product IDS Primary Antibody
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- Application Notes
- WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- IDS (Iduronate 2-Sulfatase (IDS))
- Alternative Name
- Iduronate 2 sulfatase (IDS Products)
- Synonyms
- mps2 antibody, sids antibody, zgc:158245 antibody, MPS2 antibody, SIDS antibody, AW214631 antibody, iduronate 2-sulfatase antibody, IDS antibody, CpipJ_CPIJ004938 antibody, ids antibody, Ids antibody
- Background
- Synonyms:IDS, iduronate 2 sulfatase, Idursulfase Background:Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).
- Molecular Weight
- 76 kDa, 55 kDa
- Gene ID
- 3423
- UniProt
- P22304
- Pathways
- Glycosaminoglycan Metabolic Process
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