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ITGA5 antibody
ITGA5
Reactivity: Human, Mouse, Rat, Monkey
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ITGA5 Antibody
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Target
See all ITGA5 Antibodies
ITGA5
(Integrin, alpha 5 (ITGA5))
Reactivity
All reactivities for ITGA5 antibodies
Human, Mouse, Rat, Monkey
Host
All hosts for ITGA5 antibodies
Rabbit
Clonality
All clonalities for ITGA5 antibodies
Polyclonal
Conjugate
All conjugates for ITGA5 antibodies
This ITGA5 antibody is un-conjugated
Application
All applications for ITGA5 antibodies
Western Blotting (WB), ELISA
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
integrin, alpha 5
Isotype
IgG
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Discover our top product ITGA5 Primary Antibody
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Application Details
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Application Notes
WB: 1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for ITGA5
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Target
ITGA5
(Integrin, alpha 5 (ITGA5))
Alternative Name
Integrin alpha-5 (ITGA5 Products )
Synonyms
ITGA5 antibody, Cd49e antibody, Fnra antibody, VLA5 antibody, CD49e antibody, FNRA antibody, VLA5A antibody, Itga5_retired antibody, integrin subunit alpha 5 antibody, integrin alpha 5 (fibronectin receptor alpha) antibody, ITGA5 antibody, Itga5 antibody
Background
Synonyms:CD49e, FNRA, Integrin alpha 5, Integrin alpha F, ITGA5, VLA 5, VLA5A Background:Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site(site 2) which is distinct from the classical ligand-binding site(site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1(PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1(FBN1) and mediates R-G-D-dependent cell adhesion to FBN1(PubMed:12807887, PubMed:17158881).
Molecular Weight
120 kDa
UniProt
P08648
Pathways
Integrin Complex
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