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MAML1 antibody
MAML1
Reactivity: Human, Mouse, Rat
ELISA, WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAML1 Antibody
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Target
See all MAML1 Antibodies
MAML1
(Mastermind-Like 1 (MAML1))
Reactivity
All reactivities for MAML1 antibodies
Human, Mouse, Rat
Host
All hosts for MAML1 antibodies
Rabbit
Clonality
All clonalities for MAML1 antibodies
Polyclonal
Conjugate
All conjugates for MAML1 antibodies
This MAML1 antibody is un-conjugated
Application
All applications for MAML1 antibodies
ELISA, Western Blotting (WB)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
mastermind-like 1(Drosophila)
Isotype
IgG
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Discover our top product MAML1 Primary Antibody
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Application Details
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Application Notes
WB: 1:500-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for MAML1
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Target
MAML1
(Mastermind-Like 1 (MAML1))
Alternative Name
MAML1 (MAML1 Products )
Synonyms
mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
Background
Synonyms:KIAA0200 Background:Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
Molecular Weight
108-120kd
Gene ID
9794
UniProt
Q92585
Pathways
Notch Signaling , Regulation of Muscle Cell Differentiation , Skeletal Muscle Fiber Development
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