OFD1 antibody

Catalog No. ABIN7117129

Product Details anti-OFD1 Antibody

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OFD1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: oral-facial-digital syndrome 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for OFD1

Target: OFD1 (Oral-Facial-Digital Syndrome 1 (OFD1))

Alternative Name: OFD1 (OFD1 Products)

Synonyms: 71-7A antibody, CXorf5 antibody, JBTS10 antibody, RP23 antibody, SGBS2 antibody, RGD1562231 antibody, OFD1, centriole and centriolar satellite protein antibody, OFD1 antibody, ofd1 antibody, Ofd1 antibody

Background: Synonyms:CXorf5 Background:Component of the centrioles controlling mother and daughter centrioles length. Recruits to the centriole IFT88 and centriole distal appendage-specific proteins including CEP164. Involved in the biogenesis of the cilium, a centriole-associated function. The cilium is a cell surface projection found in many vertebrate cells required to transduce signals important for development and tissue homeostasis. Plays an important role in development by regulating Wnt signaling and the specification of the left-right axis. Only OFD1 localized at the centriolar satellites is removed by autophagy, which is an important step in the ciliogenesis regulation(By similarity).

Molecular Weight: 43 kDa

Gene ID: 8481

UniProt: O75665

Pathways: M Phase