RAD17 antibody

Catalog No. ABIN7118250

This anti-RAD17 antibody is a Rabbit Polyclonal antibody detecting RAD17 in WB, ELISA, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for RAD17 antibody (ABIN7118250)

Target: RAD17

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAD17 Antibody

Purpose: RAD17 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RAD17 homolog(S. pombe)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for RAD17

Target: RAD17

Alternative Name: RAD17

Background:

Synonyms: Cell cycle checkpoint protein RAD17 (hRad17)|RF-C/activator 1 homolog|RAD17|R24L

Background: Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Molecular Weight: 71 kDa

Gene ID: 5884

UniProt: O75943