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ARHGEF4 antibody

ARHGEF4 Reactivity: Human, Mouse ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7118493
$433.85
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 10 to 13 Business Days
  • Target See all ARHGEF4 Antibodies
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Reactivity
    • 37
    • 11
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 7
    • 3
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF4 antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    Rho guanine nucleotide exchange factor(GEF) 4
    Isotype
    IgG
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Alternative Name
    ARHGEF4 (ARHGEF4 Products)
    Synonyms
    ARHGEF4 antibody, ASEF antibody, ASEF1 antibody, GEF4 antibody, STM6 antibody, 9330140K16Rik antibody, Asef antibody, ENSMUSG00000070955 antibody, Rho guanine nucleotide exchange factor 4 antibody, uncharacterized LOC100470646 antibody, rho guanine nucleotide exchange factor 4 antibody, Rho guanine nucleotide exchange factor (GEF) 4 antibody, ARHGEF4 antibody, arhg4 antibody, LOC100470646 antibody, LOC100544917 antibody, Arhgef4 antibody
    Background
    Synonyms: KIAA1112
    Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
    Molecular Weight
    72 kDa
    Gene ID
    50649
    UniProt
    Q9NR80
    Pathways
    Neurotrophin Signaling Pathway
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