Endoglin antibody (AA 58-110)

Catalog No. ABIN707561

The Rabbit Polyclonal anti-Endoglin antibody has been validated for WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc) and IF (p). It is suitable to detect Endoglin in samples from Human, Mouse, Rat and Dog. There are 8+ publications available.

Quick Overview for Endoglin antibody (AA 58-110) (ABIN707561)

Target: Endoglin (ENG)

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Endoglin Antibody

Binding Specificity: AA 58-110

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD105

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Endoglin antibody (ABIN707561)

Bidkhori, Ahmadiankia, Matin, Heirani-Tabasi, Farshchian, Naderi-Meshkin, Shahriyari, Dastpak, Bahrami: "Chemically primed bone-marrow derived mesenchymal stem cells show enhanced expression of chemokine receptors contributed to their migration capability." in: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 14-9, (2016) (PubMed).

Wang, Emond, Flynn, Swaminathan, Kibbe: "Microparticle levels after arterial injury and NO therapy in diabetes." in: The Journal of surgical research, Vol. 200, Issue 2, pp. 722-31, (2015) (PubMed).

Gao, Zhang, Zhang, Zou, Liu: "Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro." in: Cellular and molecular neurobiology, Vol. 34, Issue 2, pp. 257-68, (2014) (PubMed).

Gierloff, Nitsche, Adam-Klages, Liebs, Hedderich, Gassling, Wiltfang, Kabelitz, Açil: "In vitro comparison of different carrier materials with rat bone marrow MSCs." in: Clinical oral investigations, Vol. 18, Issue 1, pp. 247-59, (2014) (PubMed).

Zhao, Yin, Guo, Wang, Wang, Chen: "Placental expression of VEGF is increased in pregnancies with hydatidiform mole: possible association with developing very early onset preeclampsia." in: Early human development, Vol. 89, Issue 8, pp. 583-8, (2013) (PubMed).

Long, Qiu, Wang, Yang, Jia, Xin, Wang, Han, Fei, Liu: "Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy." in: Brain research, Vol. 1532, pp. 1-13, (2013) (PubMed).

Wang, Long, Jia, Liu, Yi, Yang, Fei, Liu: "Over-expression of Mash1 improves the GABAergic differentiation of bone marrow mesenchymal stem cells in vitro." in: Brain research bulletin, Vol. 99, pp. 84-94, (2013) (PubMed).

Gao, Zhao, Song, Yang: "Expression pattern of embryonic stem cell markers in DFAT cells and ADSCs." in: Molecular biology reports, Vol. 39, Issue 5, pp. 5791-804, (2012) (PubMed).

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background:

Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Gene ID: 2022

UniProt: P17813