Endoglin antibody (AA 58-110) (PE)

Catalog No. ABIN707571

Cited in 2+ publications. The PE-conjugated Rabbit Polyclonal anti-Endoglin antibody (ABIN707571) specifically detects Endoglin in WB, FACS, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for Endoglin antibody (AA 58-110) (PE) (ABIN707571)

Target: Endoglin (ENG)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-Endoglin Antibody (PE)

Binding Specificity: AA 58-110

Purpose: CD105 Polyclonal Antibody, PE Conjugated

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD105

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Endoglin antibody (PE) (ABIN707571)

Gierloff, Nitsche, Adam-Klages, Liebs, Hedderich, Gassling, Wiltfang, Kabelitz, Açil: "In vitro comparison of different carrier materials with rat bone marrow MSCs." in: Clinical oral investigations, Vol. 18, Issue 1, pp. 247-59, (2014) (PubMed).

Gao, Zhang, Zhang, Zou, Liu: "Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro." in: Cellular and molecular neurobiology, Vol. 34, Issue 2, pp. 257-68, (2014) (PubMed).

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105

Background:

Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Molecular Weight: 70kDa

Gene ID: 2022

UniProt: P17813