TMPRSS2 antibody (AA 110-360)

Catalog No. ABIN7120185

This anti-TMPRSS2 antibody is a Rabbit Polyclonal antibody detecting TMPRSS2 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for TMPRSS2 antibody (AA 110-360) (ABIN7120185)

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TMPRSS2 Antibody

Binding Specificity: AA 110-360

Purpose: TMPRSS2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 110-360aa,extra-cellular domain

Immunogen: transmembrane protease, serine 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2

Background:

Synonyms: Transmembrane protease serine 2|Serine protease 10|Transmembrane protease serine 2 non-catalytic chain|Transmembrane protease serine 2 catalytic chain|TMPRSS2|PRSS10

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 52 kDa

Gene ID: 7113

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome